Like in the first game, Dungeon Keeper 2 has a variety of maps where multiple Keepers can do battle. Notably, unlike Dungeon Keeper, the mode to play against computer players is available without tweaking, called "Skirmish".
From version 1.51, cheats do not work in multiplayer.
Unlike Dungeon Keeper, the host of a game can now change certain rules. These include details such as the availability of certain objects, game speed, etc.